Description

cis-1,2-Cyclooctanediol is a versatile eight-membered cyclic diol characterized by its specific stereochemistry, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its rigid, medium-ring structure is crucial for constructing complex molecular architectures, particularly in pharmaceutical and specialty chemical research. This compound is essential for chemists and manufacturers in the fine chemical, agrochemical, and material science industries who require high-purity, stereodefined intermediates for asymmetric synthesis and ligand development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst & Ligand Synthesis: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Polymer & Material Science: Functions as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Agrochemical Research: Employed in the development of new, stereospecific pesticides and plant growth regulators.
• Flavor & Fragrance Chemistry: Acts as an intermediate for synthesizing specific odorants and flavor compounds with defined stereochemistry.
• Academic & Industrial R&D: A fundamental tool in methodological organic chemistry research for studying ring strain and conformational analysis.

Basic Information

Product Name	cis-1,2-Cyclooctanediol
CAS No.	27607-33-6
Molecular Formula	C₈H₁₆O₂
Molecular Weight	144.21 g/mol
Synonyms	(1R,2S)-1,2-Cyclooctanediol; (1S,2R)-1,2-Cyclooctanediol; cis-Cyclooctane-1,2-diol; (1R,2S)-Cyclooctane-1,2-diol; (1S,2R)-Cyclooctane-1,2-diol; 1,2-cis-Cyclooctanediol; Cyclooctane-cis-1,2-diol; 1,2-Dihydroxy-cis-cyclooctane
EINECS	Contact for details

Quality Control

Our cis-1,2-Cyclooctanediol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity and chemical identity verification, to meet the stringent requirements of research and production. A Certificate of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.