Description

3-(2-Bromo-Acetyl)-Benzoic Acid Methyl Ester is a versatile and high-purity organic building block, essential for advanced synthetic chemistry. Its core value lies in its bifunctional reactivity, featuring both a reactive bromoacetyl group and a methyl ester, making it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing benzophenone or related scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of molecular probes due to its electrophilic bromoacetyl moiety.
• Organic Synthesis Building Block: Facilitates Friedel-Crafts acylation, nucleophilic substitution, and other C-C bond-forming reactions in complex molecule assembly.
• Academic & Contract Research: A valuable reagent for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	3-(2-Bromo-Acetyl)-Benzoic Acid Methyl Ester
CAS No.	27475-19-0
Molecular Formula	C10H9BrO3
Molecular Weight	257.08 g/mol
Synonyms	Methyl 3-(2-Bromoacetyl)benzoate; 3-(Bromoacetyl)benzoic Acid Methyl Ester; 2-Bromo-1-(3-(methoxycarbonyl)phenyl)ethan-1-one; Benzoic acid, 3-(2-bromoacetyl)-, methyl ester; Methyl m-(bromoacetyl)benzoate; 3-(2-Bromoacetyl)benzoic acid methyl ester; m-(Bromoacetyl)benzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 3-(2-Bromo-Acetyl)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.