Description

1-(4-Fluoro-Phenyl)-Piperidin-2-One is a high-purity organic intermediate featuring a fluorinated aromatic ring fused to a lactam (piperidinone) structure. This compound is valued for its role as a versatile building block in advanced pharmaceutical synthesis and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atom.
• Ligand and Catalyst Development: Used in academic and industrial research to develop new ligands for metal-catalyzed reactions or organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated organic compounds for various high-value applications.
• Material Science Research: Investigated as a monomer or building block for novel polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-Piperidin-2-One
CAS No.	27471-40-5
Molecular Formula	C11H12FNO
Molecular Weight	193.22 g/mol
Synonyms	4'-Fluoro-2-piperidinone; 1-(4-Fluorophenyl)piperidin-2-one; 2-Piperidinone, 1-(4-fluorophenyl)-; 4-Fluorophenylpiperidin-2-one; N-(4-Fluorophenyl)-2-piperidinone; 1-(p-Fluorophenyl)-2-piperidinone; 27471-40-5
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-Piperidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.