Description

2-Pyrimidinecarboxaldehyde is a versatile heterocyclic building block and key synthetic intermediate essential for advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides where the pyrimidine core imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Pyrimidinecarboxaldehyde
CAS No.	27427-92-5
Molecular Formula	C5H4N2O
Molecular Weight	108.10 g/mol
Synonyms	Pyrimidine-2-carboxaldehyde; 2-Formylpyrimidine; 2-Pyrimidinecarbaldehyde; Pyrimidine-2-carbaldehyde; 2-Carboxaldehydepyrimidine; 2-Pyrimidylaldehyde; 2-Pyrimidine aldehyde; 2-Pyrimidinecarbonal
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarboxaldehyde is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.