Description

3-Hydroxy-2-Methylbutanoic Acid is a valuable chiral hydroxy acid building block with significant utility in advanced organic synthesis. Its importance lies in its role as a key intermediate for the production of pharmaceuticals, agrochemicals, and high-value flavor and fragrance compounds. This product is essential for research institutions and industrial manufacturers in the pharmaceutical, fine chemical, and flavor industries seeking to develop or produce enantiomerically pure substances.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and neurological pathways.
• Agrochemical Synthesis: Used in the manufacture of chiral herbicides, fungicides, and plant growth regulators, where stereochemistry impacts biological activity.
• Flavor & Fragrance Industry: Serves as a building block for creating natural-identical flavor compounds and aroma chemicals, contributing to complex sensory profiles.
• Fine Chemical Production: Employed in asymmetric synthesis and as a starting material for ligands, catalysts, and other specialty organic compounds.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway research.
• Polymer Modification: Can be incorporated into polymer chains to introduce hydroxyl functionality, altering material properties like hydrophilicity and biodegradability.

Basic Information

Product Name	3-Hydroxy-2-Methylbutanoic Acid
CAS No.	27372-03-8
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	2-Methyl-3-hydroxybutyric acid; 3-Hydroxy-2-methylbutyric acid; (R/S)-3-Hydroxy-2-methylbutanoic acid; (±)-3-Hydroxy-2-methylbutanoic acid; 2-Methyl-3-hydroxybutanoic acid; α-Methyl-β-hydroxybutyric acid; 3-Hydroxy-2-methylbutyrate
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Methylbutanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.