Description

2-Formylfuran-5-Boronic Acid is a versatile bifunctional heterocyclic building block that combines an aldehyde group with a boronic acid moiety on a furan scaffold. This unique structure makes it a critical intermediate in modern synthetic chemistry, particularly for the construction of complex molecules via cross-coupling and condensation reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity, reliable intermediates for advanced R&D and production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing furan heterocycles.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic acid functionality enables efficient palladium-catalyzed cross-coupling with aryl halides to form biaryl and heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Functional Materials & OLEDs: Serves as a precursor for organic electronic materials, including ligands for metal complexes and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized as a linker or warhead component in the design of bifunctional molecules for targeted protein degradation.
• Ligand Synthesis for Catalysis: The formyl group allows for the construction of novel bidentate or tridentate ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Formylfuran-5-Boronic Acid
CAS No.	27329-70-0
Molecular Formula	C5H5BO4
Molecular Weight	139.90 g/mol
Synonyms	5-Formylfuran-2-boronic Acid; 5-Formyl-2-furanboronic Acid; 2-Furaldehyde-5-boronic Acid; 5-Borono-2-furaldehyde; 2-Formyl-5-furanboronic Acid; Furan-5-boronic acid, 2-formyl-; (5-Formylfuran-2-yl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Formylfuran-5-Boronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting cGMP, ISO, and REACH requirements for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.