Description

3-(Trifluoromethyl)Benzoylacetonitrile is a versatile fluorinated organic intermediate characterized by its reactive nitrile and ketone functional groups. This compound is valued for its role in synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the trifluoromethyl group is a key pharmacophore enhancing metabolic stability and lipophilicity. It serves as a critical building block for researchers and manufacturers developing active ingredients, advanced materials, and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl motifs for improved drug properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group contributes to efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel fluorinated polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: A valuable reagent for constructing heterocyclic compounds and other complex molecular architectures in academic and industrial R&D labs.

Basic Information

Product Name	3-(Trifluoromethyl)Benzoylacetonitrile
CAS No.	27328-86-5
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	3-(Trifluoromethyl)benzoylacetonitrile; 4-Oxo-4-[3-(trifluoromethyl)phenyl]butanenitrile; 1-[3-(Trifluoromethyl)phenyl]-1,3-butanedione-3-carbonitrile; 3-Oxo-3-[3-(trifluoromethyl)phenyl]propanenitrile; α-Acetyl-3-(trifluoromethyl)benzeneacetonitrile; 3-(Trifluoromethyl)phenacyl cyanide; m-Trifluoromethylbenzoylacetonitrile
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Benzoylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.