Description

(-)-Phyllostine CAS NO 27270-89-9 is a specific enantiomer of the fungal metabolite phyllostine, characterized by its unique bicyclic lactone structure. This compound is of significant interest in organic synthesis and pharmaceutical research as a valuable chiral building block and a precursor for complex molecule construction. It is primarily utilized by research institutions and chemical companies engaged in the development of novel bioactive compounds and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Organic Synthesis: Used as a versatile building block for constructing complex natural product analogs and other intricate molecular architectures.
• Biochemical Research: Employed in studies investigating the biological activity and mode of action of fungal metabolites.
• Asymmetric Catalysis: Acts as a potential ligand precursor or a model substrate in the development of new catalytic systems.
• Material Science Research: Investigated for its potential in creating novel polymers or functional materials with specific optical properties.

Basic Information

Item	Detail
Product Name	(-)-Phyllostine
CAS No.	27270-89-9
Molecular Formula	C8H8O4
Molecular Weight	168.15 g/mol
Synonyms	(-)-Phyllostine; Phyllostine; (3aS,6aR)-3a,4,6,6a-Tetrahydro-3a-hydroxy-4-oxofuro[3,4-b]furan-2(3H)-one; (3aS,6aR)-Hexahydro-3a-hydroxy-4-oxofuro[3,4-b]furan-2(3H)-one; Phyllostine, (-)-; L-Phyllostine; NSC 339063
EINECS	Contact for details

Quality Control

Our (-)-Phyllostine is produced and tested under strict quality management protocols. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles are provided and available upon request to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.