Description

5H-Pyrimido[4,5-B]Azepine, 6,7,8,9-Tetrahydro- (8Ci,9Ci) is a high-purity, fused heterocyclic compound serving as a critical advanced intermediate in modern organic synthesis. Its unique bicyclic structure, incorporating both pyrimidine and azepine rings, makes it a valuable scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and for exploring new chemical spaces in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate in the synthesis of specialty chemicals and advanced organic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and heterocyclic chemistry studies.

Basic Information

Item	Details
Product Name	5H-Pyrimido[4,5-B]Azepine, 6,7,8,9-Tetrahydro- (8Ci,9Ci)
CAS No.	27228-52-0
Molecular Formula	C9H11N3
Molecular Weight	161.21 g/mol
Synonyms	6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]azepine; 5H-Pyrimido[4,5-b]azepine, 6,7,8,9-tetrahydro-; Tetrahydro-5H-pyrimido[4,5-b]azepine; Pyrimidoazepine derivative; SCHEMBL218064; ZINC000253909911; AKOS015915957; A1-00826
EINECS	Contact for details

Quality Control

Every batch of 5H-Pyrimido[4,5-B]Azepine, 6,7,8,9-Tetrahydro- (8Ci,9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.