Description

Neoandrographolide is a bioactive diterpenoid lactone, a key constituent derived from the medicinal plant *Andrographis paniculata*. This compound matters for its significant pharmacological potential, offering a high-purity standard for research and development. It is primarily needed by manufacturers and researchers in the pharmaceutical, nutraceutical, and phytochemical industries focused on developing therapeutic agents and standardized botanical extracts.

Application

• Pharmaceutical Intermediates: Serves as a critical starting material or reference standard for the synthesis of novel anti-inflammatory and hepatoprotective drugs.
• Reference Standard: Used in analytical laboratories for the quality control and standardization of *Andrographis paniculata* extracts via HPLC or LC-MS methods.
• Nutraceutical Formulation: Incorporated into high-end dietary supplements aimed at supporting immune system function and overall wellness.
• Biomedical Research: Employed in *in vitro* and *in vivo* studies to investigate mechanisms of action related to its anti-inflammatory, antiviral, and anticancer properties.
• Cosmeceutical Ingredients: Explored for use in topical formulations for skin health due to its purported anti-inflammatory and antioxidant activities.
• Veterinary Pharmaceuticals: Applied in the development of animal health products for its potential therapeutic benefits.

Basic Information

Product Name	Neoandrographolide
CAS No.	27215-14-1
Molecular Formula	C26H40O8
Molecular Weight	480.59 g/mol
Synonyms	14-Deoxy-11,12-didehydroandrographolide; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; Andrographolide derivative; 14-Deoxy-11,12-didehydroandrographiside; Neoandrographiside; (4R,4aR,5R,6R,7S,8aS)-5-(Hydroxymethyl)-4,4a,5,6,7,8-hexahydro-6-hydroxy-4,7-dimethylspiro[naphthalene-1(2H),2'-oxiran]-8(3H)-one
EINECS	Contact for details

Quality Control

Our Neoandrographolide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.