Description

Butanedioic Acid, 2-Hydroxy-3-[[(2E)-3-(4-Hydroxyphenyl)-1-Oxo-2-Propen-1-Yl]Oxy]-, (2R,3R)- is a high-purity, stereochemically defined organic acid derivative of significant commercial interest. This compound matters as a versatile chiral building block and intermediate for synthesizing advanced pharmaceutical actives and fine chemicals. Industries requiring high-stereochemical fidelity, such as pharmaceutical R&D, specialty chemical synthesis, and advanced material science, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in oncology and metabolic disease research.
• Asymmetric Catalyst Ligand Precursor: Used in the development of ligands for metal-catalyzed asymmetric reactions.
• Fine Chemical Synthesis: Serves as a building block for creating specialty esters, amides, and other derivatives with specific optical activity.
• Biochemical Research: Employed in studies of enzyme inhibition and as a probe for understanding biological pathways involving hydroxycinnamic acid derivatives.
• Polymer Modification: Potential use as a functional monomer for introducing photoreactive and chiral centers into specialty polymers.

Basic Information

Product Name	Butanedioic Acid, 2-Hydroxy-3-[[(2E)-3-(4-Hydroxyphenyl)-1-Oxo-2-Propen-1-Yl]Oxy]-, (2R,3R)-
CAS No.	27174-07-8
Molecular Formula	C13H12O7
Molecular Weight	280.23 g/mol
Synonyms	(2R,3R)-2-Hydroxy-3-[(E)-3-(4-hydroxyphenyl)acryloyloxy]butanedioic acid; (2R,3R)-2-Hydroxy-3-(4-hydroxycinnamoyloxy)succinic acid; L-(+)-2-Hydroxy-3-(4-hydroxycinnamoyloxy)succinic acid; 2-Hydroxy-3-[(E)-3-(4-hydroxyphenyl)propenoyloxy]butanedioic acid (2R,3R)-; A derivative of Tartaric acid and p-Coumaric acid.
EINECS	Contact for details

Quality Control

Our Butanedioic Acid, 2-Hydroxy-3-[[(2E)-3-(4-Hydroxyphenyl)-1-Oxo-2-Propen-1-Yl]Oxy]-, (2R,3R)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2R,3R)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.