Description

1,2,3,4-Butanetetrol Tetrakis(Trifluoroacetate) is a specialized fluorinated derivative of butanetetrol (erythritol) where all four hydroxyl groups are esterified with trifluoroacetic acid. This compound is a critical high-purity synthetic intermediate and protecting group reagent, valued for its ability to introduce the trifluoroacetate moiety, which is highly labile under basic conditions. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced organic synthesis, particularly in the development of nucleosides, carbohydrates, and other complex molecules where selective deprotection is required.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially antiviral and anticancer nucleoside analogs.
• Carbohydrate Chemistry: Used as a protecting group reagent for hydroxyl groups in the synthesis of complex sugars and glycomimetics.
• Polymer Science: Serves as a monomer or cross-linking agent for creating specialty fluorinated polymers with unique solubility and surface properties.
• Chemical Research: Employed in organic methodology development as a model substrate for studying esterification, transesterification, and deprotection kinetics.
• Material Science: Potential use in the surface modification of materials to impart fluorinated characteristics, such as enhanced hydrophobicity or chemical resistance.
• Agrochemical Synthesis: An intermediate in the production of advanced, high-performance fluorinated agrochemicals.

Basic Information

Product Name	1,2,3,4-Butanetetrol Tetrakis(Trifluoroacetate)
CAS No.	27088-70-6
Molecular Formula	C12H8F12O8
Molecular Weight	508.17 g/mol
Synonyms	Erythritol Tetrakis(Trifluoroacetate); 1,2,3,4-Tetrakis-O-(trifluoroacetyl)butane; Butane-1,2,3,4-tetrayl tetra(2,2,2-trifluoroacetate); Tetrakis(trifluoroacetyl)erythritol; meso-Erythritol tetratrifluoroacetate; Erythritol, tetra(trifluoroacetate); 1,2,3,4-Butanetetrol, tetra(trifluoroacetate)
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Butanetetrol Tetrakis(Trifluoroacetate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.