Description

5-Chloro-2,6-Difluoropyrimidin-4-Amine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated pyrimidine structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Active Ingredient Development: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Precursor: Serves as a building block for creating specialized polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Chloro-2,6-Difluoropyrimidin-4-Amine
CAS No.	27078-72-4
Molecular Formula	C4H2ClF2N3
Molecular Weight	165.53 g/mol
Synonyms	4-Amino-5-chloro-2,6-difluoropyrimidine; 5-Chloro-2,6-difluoropyrimidin-4-ylamine; 2,6-Difluoro-5-chloropyrimidin-4-amine; 4-Pyrimidinamine, 5-chloro-2,6-difluoro-; 5-Chloro-2,6-difluoro-4-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,6-Difluoropyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The container must be kept tightly closed in a dry and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.