Description

Ethyl 3-Hydroxybicyclo[3.1.0]Hexane-6-Carboxylate is a high-value, functionalized bicyclic ester compound that serves as a critical chiral building block in advanced organic synthesis. Its unique strained bicyclo[3.1.0]hexane scaffold, combined with hydroxyl and ester functionalities, makes it an indispensable intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Building block for creating novel pesticides, herbicides, and fungicides with enhanced activity and selectivity.
• Advanced Material Precursor: Used in the synthesis of specialized polymers, liquid crystals, and organic electronic materials requiring rigid, functionalized cores.
• Asymmetric Catalysis & Ligand Development: Serves as a starting material for synthesizing novel chiral ligands and catalysts used in enantioselective transformations.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, particularly in reactions involving strained ring systems and stereocontrol.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex, naturally-derived odorants and flavor compounds.

Basic Information

Product Name	Ethyl 3-Hydroxybicyclo[3.1.0]Hexane-6-Carboxylate
CAS No.	26786-36-7
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	Ethyl 3-Hydroxybicyclo[3.1.0]hexane-6-carboxylate; 6-Carbethoxy-3-hydroxybicyclo[3.1.0]hexane; 3-Hydroxybicyclo[3.1.0]hexane-6-carboxylic Acid Ethyl Ester; Bicyclo[3.1.0]hexane-6-carboxylic Acid, 3-Hydroxy-, Ethyl Ester; Ethyl 3-Hydroxy-6-bicyclo[3.1.0]hexanecarboxylate
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Production is conducted under controlled environments, and every batch of Ethyl 3-Hydroxybicyclo[3.1.0]Hexane-6-Carboxylate is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.