Description

α-D-Gulofuranose, 1,2:5,6-Bis-o-(1-Methylethylidene)-, 3-Acetate is a high-purity, protected carbohydrate derivative, specifically a diacetonide-acetate of D-gulose. This compound is a critical chiral building block and synthetic intermediate in advanced organic synthesis, valued for its defined stereochemistry and protective group strategy. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, nucleosides, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly nucleoside analogs and carbohydrate-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific sugar moieties are required for bioactivity.
• Fine Chemical Production: Acts as a versatile starting material for the preparation of specialty chemicals, flavors, and fragrances requiring precise stereocontrol.
• Glycochemistry Research: Essential for academic and industrial research in glycoscience, including the study of carbohydrate-protein interactions and the synthesis of complex oligosaccharides.
• Process Chemistry: Employed in route scouting and scale-up processes for the efficient, multi-step synthesis of target molecules in a GMP or non-GMP environment.

Basic Information

Product Name	α-D-Gulofuranose, 1,2:5,6-Bis-o-(1-Methylethylidene)-, 3-Acetate
CAS No.	26775-14-4
Molecular Formula	C14H22O7
Molecular Weight	302.32 g/mol
Synonyms	1,2:5,6-Di-O-isopropylidene-α-D-gulofuranose 3-acetate; 3-O-Acetyl-1,2:5,6-di-O-isopropylidene-α-D-gulofuranose; Diacetone gulofuranose 3-acetate; 1,2:5,6-Di-O-(1-methylethylidene)-α-D-gulofuranose 3-acetate; α-D-Gulofuranose, 1,2:5,6-bis-O-(1-methylethylidene)-, 3-acetate; 3-Acetyl-1,2:5,6-di-O-isopropylidene-α-D-gulofuranose
EINECS	Contact for details

Quality Control

Our α-D-Gulofuranose, 1,2:5,6-Bis-o-(1-Methylethylidene)-, 3-Acetate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and optical rotation to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.