Description

2-Methoxy-1-(4'-Trifluoromethyl)Phenylethanone is a specialized aromatic ketone building block featuring a methoxy and a trifluoromethyl substituent. This compound is valued for its unique electronic properties, which make it a versatile intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly those requiring the introduction of fluorine-containing motifs to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the creation of novel chemical libraries.
• Fluorine Chemistry: An important building block for introducing the CF3 group into more complex molecular architectures, a common strategy in modern medicinal chemistry.

Basic Information

Product Name	2-Methoxy-1-(4'-Trifluoromethyl)Phenylethanone
CAS No.	26771-69-7
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)-2-methoxyethan-1-one; 2-Methoxy-1-[4-(trifluoromethyl)phenyl]ethanone; 4'-Trifluoromethyl-2-methoxyacetophenone; 2-Methoxy-4'-(trifluoromethyl)acetophenone; α-Methoxy-4-(trifluoromethyl)acetophenone; p-(Trifluoromethyl)phenacyl methyl ether
EINECS	Contact for details

Quality Control

Our 2-Methoxy-1-(4'-Trifluoromethyl)Phenylethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.