Description

2-Bromo-4-Iodotoluene is a halogenated toluene derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring both bromine and iodine substituents, makes it a critical intermediate for constructing complex molecules through selective cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the bromo and iodo groups enable further functionalization.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, facilitating carbon-carbon bond formation in complex molecule assembly.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	2-Bromo-4-Iodotoluene
CAS No.	26670-89-3
Molecular Formula	C7H6BrI
Molecular Weight	296.93 g/mol
Synonyms	1-Bromo-2-methyl-5-iodobenzene; 2-Methyl-4-iodophenyl bromide; 4-Iodo-2-bromotoluene; Toluene, 2-bromo-4-iodo-; 2-Bromo-4-iodo-1-methylbenzene; 5-Iodo-2-bromotoluene; (2-Bromo-4-iodophenyl)methane
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Iodotoluene is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with global regulatory frameworks, and our quality commitment aligns with cGMP principles where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.