Description

4-Methyl-2,5-Diphenyl-1,3,2-Oxazaborolidine is a specialized organoboron compound that serves as a versatile chiral reagent and catalyst in asymmetric synthesis. Its value lies in enabling high stereoselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, which is essential for producing enantiomerically pure intermediates. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Catalysis: Employed as a chiral catalyst or ligand in enantioselective reductions, aldol reactions, and Diels-Alder cycloadditions.
• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex, chiral molecular architectures in API development.
• Organic Synthesis Research: Used in academic and industrial R&D for methodological studies in stereocontrolled synthesis.
• Material Science: Potential precursor for creating novel boron-containing polymers or functional materials with specific optical properties.
• Agrochemical Synthesis: Used in the research and production of chiral active ingredients for crop protection agents.

Basic Information

Product Name	4-Methyl-2,5-Diphenyl-1,3,2-Oxazaborolidine
CAS No.	26535-25-1
Molecular Formula	C16H16BNO
Molecular Weight	249.12 g/mol
Synonyms	2,5-Diphenyl-4-methyl-1,3,2-oxazaborolidine; 4-Methyl-2,5-diphenyl-1,3,2-oxazaborolidine; Oxazaborolidine, 4-methyl-2,5-diphenyl-; (4R)-4-Methyl-2,5-diphenyl-1,3,2-oxazaborolidine; (4S)-4-Methyl-2,5-diphenyl-1,3,2-oxazaborolidine; CBS Catalyst (Corey-Bakshi-Shibata catalyst) derivative; Chiral oxazaborolidine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Methyl-2,5-Diphenyl-1,3,2-Oxazaborolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistent enantiomeric excess where applicable. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Chiral Purity (Enantiomeric Excess)	Available for specific grades (R or S)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.