Description

2-Butyl-4-Methyl-5-Phenyl-1,3,2-Oxazaborolidine is a specialized organoboron compound that serves as a highly effective chiral catalyst and reagent in asymmetric synthesis. Its value lies in enabling the production of enantiomerically pure intermediates, which are critical for the development of pharmaceuticals and advanced materials. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to improve the efficiency and selectivity of their synthetic routes.

Application

• As a chiral catalyst in the asymmetric reduction of prochiral ketones to enantiomerically enriched alcohols.
• As a key reagent in the synthesis of pharmaceutical intermediates, particularly for active pharmaceutical ingredients (APIs) requiring high optical purity.
• For use in methodology development within academic and industrial organic chemistry research laboratories.
• In the preparation of specialty fine chemicals and agrochemicals where stereochemical control is paramount.
• As a Lewis acid catalyst in various carbon-carbon and carbon-heteroatom bond-forming reactions.

Basic Information

Product Name	2-Butyl-4-Methyl-5-Phenyl-1,3,2-Oxazaborolidine
CAS No.	26535-24-0
Molecular Formula	C₁₄H₂₀BNO
Molecular Weight	229.13 g/mol
Synonyms	2-Butyl-4-methyl-5-phenyl-1,3,2-oxazaborolidine; (S)-2-Butyl-4-methyl-5-phenyl-1,3,2-oxazaborolidine; (R)-2-Butyl-4-methyl-5-phenyl-1,3,2-oxazaborolidine; CBS Catalyst; Corey-Bakshi-Shibata Catalyst; Oxazaborolidine Catalyst; B-Methyl CBS; 1,3,2-Oxazaborolidine, 2-butyl-4-methyl-5-phenyl-
EINECS	Contact for details

Quality Control

Our 2-Butyl-4-Methyl-5-Phenyl-1,3,2-Oxazaborolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high performance as a chiral auxiliary. Each lot is characterized by advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0% (for specified enantiomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.