Description

2,5-Diphenyl-1,3,2-oxazaborolidine is a specialized organoboron compound that serves as a versatile reagent and catalyst in advanced organic synthesis. Its value lies in its ability to facilitate stereoselective transformations, making it a critical component for producing high-value, optically active intermediates. This chemical is essential for research and development laboratories, as well as production facilities in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular control is paramount.

Application

• Asymmetric Catalysis: Employed as a chiral catalyst or catalyst precursor in enantioselective reduction and carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of active pharmaceutical ingredients (APIs), particularly for creating chiral centers in drug molecules.
• Agrochemical Research: Applied in the synthesis of novel, biologically active compounds for crop protection and pest control.
• Material Science: Investigated as a building block or curing agent for advanced polymeric materials with specific optical or electronic properties.
• Academic & Industrial R&D: A key reagent for methodological development in organic chemistry and process optimization.

Basic Information

Product Name	2,5-Diphenyl-1,3,2-oxazaborolidine
CAS No.	26535-22-8
Molecular Formula	C15H14BNO
Molecular Weight	235.09 g/mol
Synonyms	2,5-Diphenyl-1,3,2-oxazaborolidine; 1,3,2-Oxazaborolidine, 2,5-diphenyl-; Diphenyloxazaborolidine; CBS Catalyst (Corey-Bakshi-Shibata catalyst) derivative; Oxazaborolidine catalyst; B-Phenyloxazaborolidine; (S)- or (R)-2,5-Diphenyl-1,3,2-oxazaborolidine (enantiomeric forms)
EINECS	Contact for details

Quality Control

Our 2,5-Diphenyl-1,3,2-oxazaborolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality management system is designed to meet the rigorous standards required for research and industrial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.