Description

Aesculuside B CAS NO 26339-92-4 is a bioactive triterpenoid saponin compound derived from the horse chestnut tree (*Aesculus hippocastanum*). This high-purity reference standard is critical for ensuring analytical accuracy and reproducibility in research and development. It is primarily sought by the pharmaceutical, nutraceutical, and academic research sectors for its role in analytical method development, quality control, and biological activity studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of herbal extracts and finished products in quality control laboratories.
• Bioactivity Research: Serves as a key compound in pharmacological studies investigating anti-inflammatory, venotonic, and vascular protective properties.
• Nutraceutical Standardization: Employed to standardize and quantify the active saponin content in horse chestnut extract-based dietary supplements and herbal formulations.
• Analytical Method Development: Essential for developing and validating HPLC, UPLC, and LC-MS/MS methods in analytical chemistry and phytochemistry research.
• Academic & Institutional Research: Used in universities and research institutes for structural elucidation, metabolic studies, and as a teaching tool for natural product chemistry.

Basic Information

Product Name	Aesculuside B
CAS No.	26339-92-4
Molecular Formula	C55H86O24
Molecular Weight	1131.26 g/mol
Synonyms	Aescin Ib; Escin Ib; β-Escin; Escin Ia; Aesculus saponin B; Escin B; 21β-Angeloyloxy-22α-acetoxy-3β-[β-D-glucopyranosyl-(1→2)]-[β-D-glucopyranosyl-(1→4)]-β-D-glucopyranosiduronic acid-16α,28-dihydroxyolean-12-en-3β-yl ester; Horse Chestnut Saponin B
EINECS	Contact for details

Quality Control

Our Aesculuside B is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for a high-grade reference standard. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.