Description

(14R)-6β,14-Diacetoxy-2β,3β-Epoxygrayanotoxane-5,10,16-Triol is a highly specialized diterpenoid derivative belonging to the grayanotoxin family, a class of compounds known for their potent biological activity. This compound serves as a critical advanced intermediate or reference standard in pharmaceutical research and development, particularly for investigating sodium channel modulation. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in neuropharmacology, toxicology studies, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Research: As a key intermediate in the synthesis of novel grayanotoxin analogs for pharmacological studies.
• Reference Standard: For use in analytical chemistry, including HPLC, LC-MS, and NMR, to identify, quantify, and ensure the purity of related compounds in research samples.
• Neuroscience Studies: Utilized as a tool compound to study the structure-activity relationships (SAR) of voltage-gated sodium channel modulators.
• Toxicology & Safety Assessment: Employed as a certified standard for the accurate analysis of grayanotoxin-related substances in food safety and forensic toxicology.
• Fine Chemical Synthesis: Serves as a sophisticated building block for the total synthesis of complex natural products and bioactive diterpenoids.
• Academic Research: Used in university and institutional labs for fundamental research on plant-derived neurotoxins and their mechanisms of action.

Basic Information

Product Name	(14R)-6β,14-Diacetoxy-2β,3β-Epoxygrayanotoxane-5,10,16-Triol
CAS No.	26116-88-1
Molecular Formula	C24H34O9
Molecular Weight	466.52 g/mol
Synonyms	6β,14-Diacetoxy-2β,3β-epoxygrayanotoxane-5,10,16-triol; Grayanotoxin derivative; (14R)-Grayanotoxane-5,10,16-triol, 6,14-diacetate 2,3-epoxide; Diterpenoid epoxy acetate; 2β,3β-Epoxy-6β,14-diacetoxygrayanotoxane-5,10,16-triol; Acetylated grayanotoxin epoxide; Grayanotoxin XVI derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

We supply this high-purity compound with a focus on consistency and traceability. Our products undergo rigorous quality testing to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.