Description

Butanoic Acid, 2-Hydroxy-2-Methyl-3-Oxo-, (R)- (9Ci) is a chiral, multifunctional organic acid derivative that serves as a valuable building block in advanced chemical synthesis. Its unique stereochemistry and reactive functional groups make it a critical intermediate for producing high-value, optically active compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific chiral centers into complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators for enhanced efficacy and environmental safety.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals where optical purity is crucial for sensory profile and performance.
• Asymmetric Catalysis Research: Employed as a standard or ligand precursor in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Biochemical Research: Utilized in studies of enzyme mechanisms and metabolic pathways due to its structural similarity to natural keto-acid metabolites.

Basic Information

Product Name	Butanoic Acid, 2-Hydroxy-2-Methyl-3-Oxo-, (R)- (9Ci)
CAS No.	26011-30-3
Molecular Formula	C5H8O4
Molecular Weight	132.11 g/mol
Synonyms	(R)-2-Hydroxy-2-methyl-3-oxobutanoic acid; (R)-2-Methyl-3-oxobutan-2-ol-1-carboxylic acid; D-2-Hydroxy-2-methyl-3-oxobutyric acid; (R)-3-Oxo-2-hydroxy-2-methylbutyric acid; 2-Hydroxy-2-methyl-3-oxo-(R)-butanoic acid; (R)-HMB precursor; (R)-Ketopantoic acid derivative
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 2-Hydroxy-2-Methyl-3-Oxo-, (R)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure consistent chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed after opening to prevent degradation due to moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (R-enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.