Description

[1As-(1Aalpha,2Alpha,4Abeta,8Ar*)]-Octahydro-2,4A,8,8-Tetramethylcyclopropa[D]Naphthalen-3(1H)-One is a high-purity, complex polycyclic ketone of significant interest in advanced organic synthesis. This compound serves as a critical chiral intermediate for the development of novel fragrance molecules, pharmaceuticals, and specialty chemicals. It is primarily sought by R&D chemists and process development teams in the flavor & fragrance, pharmaceutical, and agrochemical industries for its unique structural framework and stereochemistry.

Application

• Fragrance & Flavor Intermediate: A key chiral building block for the synthesis of novel, high-value musk compounds and other complex aroma chemicals.
• Pharmaceutical Research: Used as a sophisticated synthetic intermediate in the discovery and development of new active pharmaceutical ingredients (APIs), particularly those with complex polycyclic structures.
• Agrochemical Synthesis: Employed in the research and production of advanced pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Organic Synthesis Reagent: Acts as a versatile starting material or intermediate in academic and industrial laboratories for methodological studies and the construction of complex natural product analogs.
• Fine Chemical Production: Utilized in the manufacture of other specialty chemicals requiring its distinct fused ring system.

Basic Information

Product Name	[1As-(1Aalpha,2Alpha,4Abeta,8Ar*)]-Octahydro-2,4A,8,8-Tetramethylcyclopropa[D]Naphthalen-3(1H)-One
CAS No.	25966-79-4
Molecular Formula	C15H24O
Molecular Weight	220.35 g/mol
Synonyms	(1aS,2S,4aR,8aR)-Octahydro-2,4a,8,8-tetramethylcyclopropa[d]naphthalen-3(1H)-one; 1aS-(1aα,2α,4aβ,8aα*))-Octahydro-2,4a,8,8-tetramethylcyclopropa[d]naphthalen-3(1H)-one; Ambroxide Precursor; Tetramethyl Cyclopropanaphthalenone; Cyclopropa[D]Naphthalen-3(1H)-One Derivative; Polycyclic Ketone Intermediate
EINECS	Contact for details

Quality Control

Our production of [1As-(1Aalpha,2Alpha,4Abeta,8Ar*)]-Octahydro-2,4A,8,8-Tetramethylcyclopropa[D]Naphthalen-3(1H)-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (GC/HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.