Description

(8α,13S)-12α,13α-Epoxy-8-Hydroxy-13-Isopropylpodocarpan-18-Oic Acid Methyl Ester is a high-purity diterpenoid derivative with a complex, functionalized podocarpane skeleton. This compound serves as a critical advanced intermediate in organic synthesis, valued for its unique stereochemistry and reactive epoxide and ester functional groups. It is primarily utilized by pharmaceutical R&D and fine chemical laboratories for the development of novel bioactive molecules and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Chemical Reference Standard: Used for analytical method development, calibration, and quality control in laboratories.
• Organic Synthesis Research: Serves as a chiral precursor for constructing complex diterpenoid and steroidal frameworks in academic and industrial settings.
• Natural Product Derivative Synthesis: Enables the semi-synthesis of modified podocarpane derivatives for structure-activity relationship (SAR) studies.
• Biochemical Probe Development: Utilized in creating tool compounds for investigating biological pathways and enzyme interactions.

Basic Information

Product Name	(8α,13S)-12α,13α-Epoxy-8-Hydroxy-13-Isopropylpodocarpan-18-Oic Acid Methyl Ester
CAS No.	25859-62-5
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	Methyl (8α,13S)-12α,13α-epoxy-8-hydroxy-13-isopropylpodocarpan-18-oate; 13-Isopropylpodocarpa-8,11,13-trien-18-oic acid, 12,13-epoxy-8-hydroxy-, methyl ester, (8α,13S)-; Podocarpic acid methyl ester derivative; 12α,13α-Epoxy-8α-hydroxy-13-isopropylpodocarpan-18-oic acid methyl ester
EINECS	Contact for details

Quality Control

Our (8α,13S)-12α,13α-Epoxy-8-Hydroxy-13-Isopropylpodocarpan-18-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.