Description

Azoxymethane is a potent alkylating agent and a well-characterized chemical carcinogen used extensively in biomedical research. Its primary value lies in its reliable induction of colon tumors in rodent models, making it a critical tool for studying the mechanisms of carcinogenesis and evaluating potential chemopreventive agents. This compound is essential for researchers and institutions in the fields of oncology, toxicology, and pharmaceutical development who require a consistent and high-purity agent for preclinical studies.

Application

• Preclinical Cancer Research: Standard agent for inducing colorectal cancer in rodent models (rats and mice) to study tumor biology and progression.
• Chemoprevention Studies: Used to test the efficacy of potential dietary compounds, pharmaceuticals, and nutraceuticals in preventing colon carcinogenesis.
• Toxicology and Safety Assessment: Serves as a positive control in studies investigating the carcinogenic potential of other substances or environmental factors.
• Molecular Pathway Analysis: Facilitates research into specific genetic and biochemical pathways involved in the initiation and promotion of colon cancer.
• Drug Efficacy Testing: Employed in animal models to evaluate the anti-tumor activity of novel therapeutic candidates targeting colorectal cancer.

Basic Information

Product Name	Azoxymethane
CAS No.	25843-45-2
Molecular Formula	C2H6N2O
Molecular Weight	74.08 g/mol
Synonyms	Methylazoxymethanol acetate; Azoxymethane; AOM; Diazene, 1,1'-dimethyl-, 1-oxide; NSC 9411; Methylazoxymethyl acetate; DMN-O; 1,1-Dimethyl-1-oxohydrazine
EINECS	Contact for details

Quality Control

Our Azoxymethane is produced and handled under strict quality protocols to ensure the consistency and reliability required for sensitive research applications. Each batch undergoes comprehensive analytical testing, including purity assay and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.