Description

3-(Trifluoromethyl)Benzyl Mercaptan is a specialized organosulfur compound featuring a benzyl mercaptan core substituted with a trifluoromethyl group. This unique structure makes it a valuable intermediate for introducing sulfur-containing, fluorinated motifs into target molecules, which is critical for modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral thiol ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Incorporated into polymers and advanced materials to impart specific surface properties, adhesion, or corrosion resistance.
• Chemical Research: A versatile reagent for organic synthesis, used in nucleophilic substitution reactions, thioether formation, and as a protecting group precursor.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing sulfur-containing aroma chemicals, though at high purity grades.

Basic Information

Product Name	3-(Trifluoromethyl)Benzyl Mercaptan
CAS No.	25697-55-6
Molecular Formula	C8H7F3S
Molecular Weight	192.20 g/mol
Synonyms	α-Toluenethiol, 3-(trifluoromethyl)-; (3-(Trifluoromethyl)phenyl)methanethiol; 3-(Trifluoromethyl)benzylthiol; m-(Trifluoromethyl)benzyl mercaptan; 1-(Trifluoromethyl)-3-(mercaptomethyl)benzene; 3-Trifluoromethylbenzyl mercaptan; Benzenemethanethiol, 3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Benzyl Mercaptan is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.500 - 1.510
Density	1.28 - 1.32 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.