Description

(E)-5-[(1S,4Aα)-Decahydro-5β-Hydroxymethyl-5,8A-Dimethyl-2-Methylenenaphthalen-1β-Yl]-3-Methyl-2-Pentenoic Acid is a high-purity, complex diterpenoid carboxylic acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block and a key intermediate for the research and development of novel bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating complex, stereochemically defined structures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory or metabolic disease research.
• Agrochemical Synthesis: Used in the development of advanced, high-specificity plant growth regulators or environmentally benign pesticides.
• Chemical Biology Probe: Acts as a scaffold or ligand in the design of molecular probes for studying enzyme mechanisms or receptor interactions.
• Advanced Material Research: Potential monomer or additive for creating specialty polymers with unique thermal or mechanical properties.
• Academic & Institutional Research: Employed in university and government labs for methodological studies in total synthesis and stereoselective transformations.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(E)-5-[(1S,4Aα)-Decahydro-5β-Hydroxymethyl-5,8A-Dimethyl-2-Methylenenaphthalen-1β-Yl]-3-Methyl-2-Pentenoic Acid
CAS No.	25671-16-3
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	5-[(1S,4aα)-Decahydro-5β-(hydroxymethyl)-5,8a-dimethyl-2-methylenenaphthalen-1β-yl]-3-methyl-2-pentenoic acid, (E)-; (1S,4aR,5R,8aS)-5-[(1E)-4-Carboxy-2-buten-2-yl]-5-(hydroxymethyl)-1,4a-dimethyl-6-methylenedecahydronaphthalene; Podocarpic Acid derivative; Diterpenoid Carboxylic Acid Intermediate.
EINECS	Contact for details

Quality Control

Our (E)-5-[(1S,4Aα)-Decahydro-5β-Hydroxymethyl-5,8A-Dimethyl-2-Methylenenaphthalen-1β-Yl]-3-Methyl-2-Pentenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.