Description

4-Iodotetrahydro-2H-Pyran is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive iodine moiety.
• Cross-Coupling Reactions: Serves as a competent electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form carbon-carbon bonds.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and other functional materials requiring tailored heterocyclic components.
• Chemical Biology Probes: Useful for the synthesis of molecular probes and labeled compounds for biochemical and diagnostic research.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	4-Iodotetrahydro-2H-Pyran
CAS No.	25637-18-7
Molecular Formula	C5H9IO
Molecular Weight	212.03 g/mol
Synonyms	4-Iodotetrahydropyran; Tetrahydropyran-4-yl iodide; 4-Iodotetrahydropyran; 4-Iodooxane; 4-Iodotetrahydro-2H-pyran; THP-4-I; Oxan-4-yl iodide
EINECS	Contact for details

Quality Control

Our 4-Iodotetrahydro-2H-Pyran is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing specific results for purity, identity, and impurities are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.