Description

1-(2,3,4,5,6-Pentafluorophenyl)-1-Propanone is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the perfluorinated phenyl ring, making it a critical precursor for developing novel materials and active compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require high-purity, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, pesticides, and fungicides where the pentafluorophenyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and thermal stability.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis, leveraging the strong electron-withdrawing nature of the perfluoroarene group.
• Polymer & Specialty Chemical Modifier: Incorporated into polymer chains or specialty chemicals to introduce fluorine, thereby altering surface properties, chemical resistance, and durability.
• Research & Development (R&D): A valuable compound for academic and industrial R&D exploring new reactions, fluorination effects, and structure-activity relationships.

Basic Information

Product Name	1-(2,3,4,5,6-Pentafluorophenyl)-1-Propanone
CAS No.	25622-74-6
Molecular Formula	C9H5F5O
Molecular Weight	224.13 g/mol
Synonyms	Pentafluoropropiophenone; 1-Propanone, 1-(2,3,4,5,6-pentafluorophenyl)-; 2,3,4,5,6-Pentafluoropropiophenone; PFP-Propanone; α-Oxopropylpentafluorobenzene; Pentafluorobenzoyl ethane
EINECS	Contact for details

Quality Control

Our production of 1-(2,3,4,5,6-Pentafluorophenyl)-1-Propanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.