Description

4-Chlorophenyl Diethyl Orthoformate is a specialized orthoester derivative, a key building block in advanced organic synthesis. Its value lies in its role as a versatile reagent for introducing the 4-chlorophenyl group and protecting/formylating agents in complex molecule construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to create active ingredients and novel intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing chlorophenyl moieties.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the 4-chlorophenyl group is a key structural component.
• Fine Chemical Manufacturing: Serves as a versatile building block for dyes, pigments, and other performance chemicals.
• Protecting Group Chemistry: Functions as an orthoester protecting group for aldehydes and other sensitive functional groups during multi-step syntheses.
• Formylation Reagent: Employed in specific formylation reactions to introduce formyl groups into aromatic systems under controlled conditions.
• Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-Chlorophenyl Diethyl Orthoformate
CAS No.	25604-54-0
Molecular Formula	C11H15ClO3
Molecular Weight	230.69 g/mol
Synonyms	Diethyl (4-Chlorophenoxy)methanediyl Dioxide; Diethyl (4-Chlorophenoxy)orthoformate; 1-Chloro-4-(diethoxymethoxy)benzene; 4-Chlorophenol Diethyl Orthoformate; Orthoformic Acid, 4-Chlorophenyl Diethyl Ester; (4-Chlorophenoxy)methanediyl Diethyl Dioxide; NSC 403796
EINECS	Contact for details

Quality Control

Our 4-Chlorophenyl Diethyl Orthoformate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent contact with atmospheric moisture. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.