Description

1-Chloro-1,3-Cyclobutanedicarboxylic Acid Dimethyl Ester is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its unique cyclobutane ring structure, functionalized with both a chloro and diester group, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those requiring a rigid, strained cyclobutane core.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its functional groups allow for further chemical modifications.
• Organic Synthesis Building Block: Serves as a precursor for synthesizing more complex cyclobutane derivatives, lactones, and other specialty chemicals.
• Material Science Research: Investigated for the preparation of monomers or additives that can impart specific properties to polymers.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new chemical reactions, such as ring-opening or cross-coupling transformations.

Basic Information

Product Name	1-Chloro-1,3-Cyclobutanedicarboxylic Acid Dimethyl Ester
CAS No.	25596-64-9
Molecular Formula	C9H13ClO4
Molecular Weight	220.65 g/mol
Synonyms	Dimethyl 1-Chloro-1,3-cyclobutanedicarboxylate; 1-Chloro-cyclobutane-1,3-dicarboxylic Acid Dimethyl Ester; 1-Chloro-1,3-cyclobutanedicarboxylic Acid Methyl Ester; Methyl 1-Chloro-1,3-cyclobutanedicarboxylate; Cyclobutanedicarboxylic Acid, 1-Chloro-, Dimethyl Ester; 25596-64-9; 1-Chlorocyclobutane-1,3-dicarboxylic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 1-Chloro-1,3-Cyclobutanedicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality parameters are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.