Description

(8α)-8,12α-Epoxy-13α,14α-Dihydroxy-13-Isopropylpodocarpan-18-Oic Acid Methyl Ester is a high-purity diterpenoid derivative, a key intermediate in advanced organic synthesis and pharmaceutical research. This compound is valued for its complex, functionalized podocarpane skeleton, which serves as a versatile scaffold for developing novel bioactive molecules. It is primarily sought by research institutions and fine chemical manufacturers specializing in medicinal chemistry, natural product synthesis, and the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel drug candidates and analogs of natural products.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore new therapeutic targets.
• Natural Product Synthesis: Acts as a key intermediate in the total or semi-synthesis of complex diterpenoid natural products.
• Reference Standard: Employed as an analytical standard in quality control and method development for related compounds.
• Biochemical Research: Investigated for potential biological activities inherent to the functionalized podocarpane structure.
• Fine Chemical Synthesis: Utilized in the production of specialty chemicals requiring a specific, complex chiral framework.

Basic Information

Product Name	(8α)-8,12α-Epoxy-13α,14α-Dihydroxy-13-Isopropylpodocarpan-18-Oic Acid Methyl Ester
CAS No.	25594-18-7
Molecular Formula	C21H30O6
Molecular Weight	378.46 g/mol
Synonyms	Methyl (8α,12α,13α,14α)-8,12-Epoxy-13,14-dihydroxy-13-(1-methylethyl)podocarpan-18-oate; 13-Isopropylpodocarpa-8,11,13-trien-18-oic acid, 8,12-epoxy-13,14-dihydroxy-, methyl ester, (8α,12α,13α,14α)-; Methyl 8α,12α-epoxy-13α,14α-dihydroxy-13-isopropylpodocarpan-18-oate; Podocarpic acid derivative methyl ester; Diterpenoid epoxy diol methyl ester.
EINECS	Contact for details

Quality Control

Our (8α)-8,12α-Epoxy-13α,14α-Dihydroxy-13-Isopropylpodocarpan-18-Oic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound should be handled in accordance with good laboratory practices to maintain its stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.