Description

4-(4-Fluorobenzoyl)Piperidine Hydrochloride is a high-purity organic salt compound, recognized as a key pharmaceutical intermediate and versatile building block in advanced organic synthesis. Its value lies in its defined structure, which is critical for ensuring the consistency and efficacy of final active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development and production of new therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring the piperidine scaffold with a fluorinated benzoyl moiety.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides, leveraging its fluorine-containing aromatic system.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in biochemical research and the study of biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects and scale-up production for clients in the fine chemical sector.
• Academic & R&D Laboratories: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-(4-Fluorobenzoyl)Piperidine Hydrochloride
CAS No.	25519-78-2
Molecular Formula	C12H14FNO•HCl
Molecular Weight	243.70 g/mol (Free base: 207.24 g/mol)
Synonyms	1-(4-Fluorobenzoyl)piperidine hydrochloride; 4-Fluorobenzoylpiperidine HCl; Piperidine, 1-(4-fluorobenzoyl)-, hydrochloride; 4-Fluorophenyl piperidin-1-yl methanone hydrochloride; 4-Fluoro-1-(piperidine-1-carbonyl)benzene hydrochloride; 25519-78-2; 4-(p-Fluorobenzoyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorobenzoyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.