Description

Bruceine A is a quassinoid compound, a class of natural products known for their significant biological activity. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of antiparasitic and anticancer agents. It serves as an essential analytical standard for quality control in the production of botanical extracts and advanced pharmaceutical intermediates. Researchers and manufacturers in the pharmaceutical, nutraceutical, and academic sectors rely on its consistent quality for reliable experimental and production outcomes.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of bruceine A in raw materials and finished products.
• Antiparasitic Research: Serves as a key active ingredient for in-vitro and in-vivo studies targeting parasites such as malaria and leishmania.
• Oncology Research: Investigated for its potential cytotoxic and apoptosis-inducing effects in various cancer cell line studies.
• Botanical Extract Standardization: Essential for the quality control and standardization of extracts derived from Brucea javanica and related species.
• Bioactive Compound Isolation: Used as a marker compound to guide the isolation and purification processes in natural product chemistry.
• Formulation Development: Employed in pre-formulation studies and stability testing for new drug formulations containing quassinoids.

Basic Information

Product Name	Bruceine A
CAS No.	25514-31-2
Molecular Formula	C20H28O9
Molecular Weight	412.43 g/mol
Synonyms	Bruceine A; Yadanzioside A; (1S,2R,6S,7S,8S,11S,12R,13S,15R,17S)-11,12,13,15-Tetrahydroxy-6,7-epoxy-2,8,17-trimethyl-14,18-dioxapentacyclo[11.7.0.0²,¹⁰.0⁵,⁹.0¹³,¹⁷]icosa-4,9-dien-3-one; NSC 165563; BRN 2936448
EINECS	Contact for details

Quality Control

Every batch of Bruceine A is produced and analyzed under strict quality management protocols. Our standard grade meets high-purity specifications suitable for research and development, with comprehensive testing including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.