Description

Diethyl (Diazomethyl)Phosphonate is a versatile and highly reactive organophosphorus reagent, specifically a diazo compound, widely utilized in synthetic organic chemistry. Its primary value lies in its ability to serve as a precursor for the synthesis of phosphonates and as a key reagent in homologation reactions, such as the Corey-Chaykovsky and related transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require efficient methods for carbon-carbon and carbon-heteroatom bond formation.

Application

• Key reagent in the Corey-Chaykovsky reaction for the synthesis of epoxides and cyclopropanes.
• Precursor for generating phosphonate ylides used in Wittig-type olefination reactions.
• Building block in the synthesis of α-functionalized phosphonates, important for medicinal chemistry and drug discovery.
• Used in the preparation of heterocyclic compounds and complex molecular architectures.
• Employed in agrochemical research for creating novel active ingredients with phosphonate moieties.
• Facilitates chain homologation processes to extend carbon skeletons in organic synthesis.
• Valuable in material science for modifying surfaces or creating phosphorus-containing polymers.

Basic Information

Product Name	Diethyl (Diazomethyl)Phosphonate
CAS No.	25411-73-8
Molecular Formula	C5H11N2O3P
Molecular Weight	178.13 g/mol
Synonyms	(Diazomethyl)phosphonic Acid Diethyl Ester; Diethyl Diazomethylphosphonate; Diethyl (Diazomethyl)Phosphonate; Diazomethylphosphonic Acid Diethyl Ester; (Diazo-methyl)-phosphonic Acid Diethyl Ester; Diethyl P-Diazomethylphosphonate; Ethyl (Diazomethyl)Phosphonate; EINECS 246-980-1
EINECS	246-980-1

Quality Control

Our Diethyl (Diazomethyl)Phosphonate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and process-scale applications. Each lot is analyzed using advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and potential reactivity, it should be kept under an inert atmosphere for long-term storage and handled with appropriate safety precautions.

Specification

Item	Specification
Appearance	Yellow to orange liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.