Description

1-(3-Fluorophenyl)Imidazole is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the imidazole core and fluorine substituent impart desirable biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl-imidazole scaffold.
• Ligand & Catalyst Development: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymers, liquid crystals, and electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for developing enzyme inhibitors or receptor modulators.

Basic Information

Product Name	1-(3-Fluorophenyl)Imidazole
CAS No.	25372-42-3
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	1-(3-Fluorophenyl)-1H-imidazole; 3-Fluorophenylimidazole; 1H-Imidazole, 1-(3-fluorophenyl)-; 1-(m-Fluorophenyl)imidazole; 3-Fluoro-1-imidazol-1-ylbenzene; 1-(3-Fluorophenyl)-imidazole; 1-(3-Fluorophenyl)imidazole; 3-Fluorophenyl-1-imidazole
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.