Description

1,3,5-Trineopentyl-2-Bromobenzene is a specialized, high-purity brominated aromatic compound characterized by its sterically hindered neopentyl substituents. This unique molecular architecture makes it a valuable intermediate for advanced organic synthesis, particularly in the development of ligands, catalysts, and functional materials. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce steric bulk and specific reactivity into complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates where steric hindrance is required for metabolic stability or receptor binding.
• Ligand & Catalyst Precursor: Serves as a key building block for constructing sophisticated phosphine, N-heterocyclic carbene (NHC), and other organometallic ligands used in cross-coupling and asymmetric catalysis.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and plant growth regulators with tailored properties.
• Material Science: Acts as a monomer or functionalization agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A crucial reagent for methodological studies in organic chemistry, including Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Fine Chemical Production: Utilized in the manufacture of dyes, pigments, and other performance chemicals requiring specific bromo-aryl functionalities.

Basic Information

Product Name	1,3,5-Trineopentyl-2-Bromobenzene
CAS No.	25347-03-9
Molecular Formula	C₂₄H₄₁Br
Molecular Weight	409.49 g/mol
Synonyms	2-Bromo-1,3,5-trineopentylbenzene; Benzene, 2-bromo-1,3,5-tris(2,2-dimethylpropyl)-; 1,3,5-Tris(neopentyl)-2-bromobenzene; 2-Bromo-1,3,5-tris(2,2-dimethylpropyl)benzene; 2-Bromo-mesitylene, trineopentyl derivative; Bromomesitylene, trineopentyl-; Tris(neopentyl)bromobenzene
EINECS	Contact for details

Quality Control

Every batch of 1,3,5-Trineopentyl-2-Bromobenzene is manufactured and tested under a strict quality management system. We guarantee high purity and consistency to meet the exacting standards of research and industrial synthesis. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) documenting all relevant specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.