Description

Methyl 3-Amino-2,2-Dimethylpropanoate is a versatile amino acid ester building block characterized by its sterically hindered structure. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), peptide mimetics, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its amino ester functionality.
• Peptidomimetics & Bioactive Compounds: Serves as a constrained, non-natural amino acid analog in the design of peptide-like structures with enhanced metabolic stability.
• Organic Synthesis Reagent: Employed in various organic transformations, such as amide coupling and nucleophilic substitution reactions, due to its reactive amino group.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored properties.
• Ligand & Catalyst Preparation: Utilized in the synthesis of chiral ligands and metal complexes for asymmetric catalysis.

Basic Information

Product Name	Methyl 3-Amino-2,2-Dimethylpropanoate
CAS No.	25307-82-8
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	3-Amino-2,2-dimethylpropanoic acid methyl ester; Methyl 3-amino-2,2-dimethylpropionate; 2,2-Dimethyl-3-aminopropionic acid methyl ester; β-Aminoisobutyric acid methyl ester; 3-Amino-2,2-dimethyl-methyl propanoate; Amino dimethyl propanoate ester; Meldrum's acid derivative (contextual)
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-2,2-Dimethylpropanoate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.