Description

Benzylidene Glucose is a protected carbohydrate derivative where the glucose molecule is selectively masked with a benzylidene acetal group. This chemical modification is crucial for enabling complex synthetic transformations in organic chemistry by temporarily blocking specific hydroxyl functionalities. It serves as a versatile chiral building block and synthetic intermediate for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the synthesis of nucleosides, complex sugars, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of antiviral and anticancer nucleoside analogs.
• Carbohydrate Chemistry: Used as a protected starting material for the regioselective synthesis of complex oligosaccharides and glycoconjugates.
• Fine Chemical Synthesis: Acts as a precursor for the production of specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & R&D: Employed in research laboratories for method development in asymmetric synthesis and glycosylation reactions.
• Glycobiology Research: Useful in the study of carbohydrate-protein interactions and the development of glycomimetic drugs.

Basic Information

Product Name	Benzylidene Glucose
CAS No.	25152-90-3
Molecular Formula	C₁₃H₁₆O₆
Molecular Weight	268.26 g/mol
Synonyms	4,6-O-Benzylidene-D-glucose; 4,6-O-Benzylidene-α-D-glucopyranose; D-Glucose, 4,6-O-(phenylmethylene)-; Benzylidene-D-glucopyranose; 4,6-Benzylidene-D-glucose; 1,2,3-Tri-O-acetyl-4,6-O-benzylidene-α-D-glucopyranose (precursor derivative); α-D-Glucopyranose, 4,6-O-benzylidene-
EINECS	Contact for details

Quality Control

Our Benzylidene Glucose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Specific Rotation [α]²⁰D	+80° to +85° (c=1 in CHCl₃)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.