Description

(5α,8β,9α,10β,12β,13R,16S)-Trachyloban-18-Oic Acid is a high-purity, specialized diterpenoid carboxylic acid belonging to the trachylobane class. This compound is valued for its unique and rigid tetracyclic skeleton, making it a critical reference standard and advanced intermediate in organic synthesis and phytochemical research. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in developing novel bioactive molecules or studying natural product biosynthesis.

Application

• Pharmaceutical Research & Development: Serves as a key chiral building block or a pharmacophore model for the synthesis of novel drug candidates, particularly in anti-inflammatory or antimicrobial research.
• Reference Standard in Analytical Chemistry: Used for the identification, method development, and quantification of trachylobane diterpenoids in complex matrices via HPLC, GC-MS, or NMR.
• Natural Product Chemistry & Phytochemistry: Employed as an authentic standard for isolating and characterizing related diterpenoids from plant extracts or studying their biosynthetic pathways.
• Organic Synthesis Intermediate: Utilized in semi-synthesis to create derivatives for structure-activity relationship (SAR) studies due to its complex, functionalized ring system.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzymes or cellular receptors in mechanistic studies.

Basic Information

Product Name	(5α,8β,9α,10β,12β,13R,16S)-Trachyloban-18-Oic Acid
CAS No.	25146-40-1
Molecular Formula	C₂₀H₃₂O₂
Molecular Weight	304.47 g/mol
Synonyms	Trachyloban-18-oic acid; (-)-Trachyloban-18-oic acid; 18-Trachylobanoic acid; NSC 338250; ent-Trachyloban-18-oic acid; (13R)-ent-Trachyloban-18-oic acid; Trachylobane-18-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of (5α,8β,9α,10β,12β,13R,16S)-Trachyloban-18-Oic Acid is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, NMR, and chiral analysis to ensure identity, purity, and enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.