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(2Alpha,6Alpha,11R*)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2,6-Methano-3-Benzazocin-8-Ol CAS NO 25144-78-9


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CAS No.:25144-78-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2Alpha,6Alpha,11R*)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2,6-Methano-3-Benzazocin-8-Ol is a complex, high-purity benzazocine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and reference standard for the development of novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel analgesic and neuropharmacological agents.
  • Reference Standard: Used for analytical method development, validation, and quality control in API (Active Pharmaceutical Ingredient) manufacturing.
  • Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to explore new drug candidates.
  • Biochemical Research: Utilized in receptor binding assays and pharmacological profiling studies.
  • GMP Manufacturing: Supplied as a starting material or intermediate for the production of clinical trial materials under controlled conditions.
  • Academic Research: Employed in university laboratories for advanced studies in organic synthesis and drug discovery.

Basic Information

Product Name (2Alpha,6Alpha,11R*)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2,6-Methano-3-Benzazocin-8-Ol
CAS No. 25144-78-9
Molecular Formula C15H21NO
Molecular Weight 231.33 g/mol
Synonyms 8-Hydroxy-6,11-dimethyl-2,6-methano-3-benzazocine; 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-, (2α,6α,11R*)-; 8-OH-DMB; 8-Hydroxy-DMB; 25144-78-9; (2α,6α,11R*)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol
EINECS Contact for details

Quality Control

Our (2Alpha,6Alpha,11R*)-1,2,3,4,5,6-Hexahydro-6,11-Dimethyl-2,6-Methano-3-Benzazocin-8-Ol is produced and tested under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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