Description

(3-Chloro-Phenyl)-Methanesulfonyl Chloride is a versatile and reactive organosulfur compound that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, acting as a key electrophile for introducing the methanesulfonyl (mesyl) group and enabling further derivatization via the reactive sulfonyl chloride moiety. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the (3-chlorophenyl) moiety for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers and functional materials.
• Chemical Research: Employed as a versatile reagent for introducing sulfonyl groups and for further functionalization in complex molecule construction.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands for metal catalysis and organocatalysts.

Basic Information

Product Name	(3-Chloro-Phenyl)-Methanesulfonyl Chloride
CAS No.	24974-73-0
Molecular Formula	C7H6Cl2O2S
Molecular Weight	225.09 g/mol
Synonyms	3-Chlorophenylmethanesulfonyl chloride; 1-Chloro-3-[(chlorosulfonyl)methyl]benzene; m-Chlorophenylmethanesulfonyl chloride; (3-Chlorophenyl)methanesulfonyl chloride; α-Chloro-m-toluenesulfonyl chloride; Benzenemethanesulfonyl chloride, 3-chloro-; 3-Chlorobenzylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our (3-Chloro-Phenyl)-Methanesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.