Description

(4As)-1,2,3,4,4Aβ,7,7Aα,8,9,10,11,11Aα,12,13,13Aβ,13Bα-Hexadecahydro-7-Hydroxy-10β,11-Dimethyl-7α,13α-Methano-5H-Naphtho[2',1':4,5]Cyclohepta[1,2-B]Pyridin-5-One is a complex, high-purity organic compound characterized by its intricate polycyclic structure featuring a bridged methano group and a pyridinone moiety. This compound serves as a critical advanced intermediate or reference standard in the synthesis of novel pharmaceutical agents and fine chemicals. It is primarily required by research institutions, pharmaceutical R&D laboratories, and specialty chemical manufacturers engaged in developing new therapeutic molecules or complex organic syntheses.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex target molecules.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in research and manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Employed in advanced synthetic chemistry for constructing complex polycyclic frameworks found in natural products and specialty materials.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for the production of target compounds in pilot and commercial-scale manufacturing.

Basic Information

Product Name	(4As)-1,2,3,4,4Aβ,7,7Aα,8,9,10,11,11Aα,12,13,13Aβ,13Bα-Hexadecahydro-7-Hydroxy-10β,11-Dimethyl-7α,13α-Methano-5H-Naphtho[2',1':4,5]Cyclohepta[1,2-B]Pyridin-5-One
CAS No.	24932-15-8
Molecular Formula	C22H31NO2
Molecular Weight	341.49 g/mol
Synonyms	7-Hydroxy-10β,11-dimethyl-7α,13α-methano-5H-naphtho[2',1':4,5]cyclohepta[1,2-b]pyridin-5-one; Hexadecahydro-7-hydroxy-10,11-dimethyl-7,13-methanonaphtho[2,1-f]quinolizin-5-one; 7-Hydroxy-10,11-dimethyl-7,13-methano-5H-naphtho[2,1-f]quinolizin-5-one; 7-Hydroxy-10,11-dimethyl-7,13-methanonaphtho[2,1-f]quinolizin-5-one; 7-Hydroxy-10,11-dimethyl-7,13-methano-5H-naphtho[2',1':4,5]cyclohepta[1,2-b]pyridin-5-one; (4aS,7R,7aR,11aS,13R,13aR,13bS)-7-Hydroxy-10,11-dimethyl-4a,5,6,7,7a,8,9,10,11,11a,12,13,13a,13b-tetradecahydro-4H-7,13-methanonaphtho[2,1-f]quinolizin-5-one
EINECS	Contact for details

Quality Control

Our (4As)-1,2,3,4,4Aβ,7,7Aα,8,9,10,11,11Aα,12,13,13Aβ,13Bα-Hexadecahydro-7-Hydroxy-10β,11-Dimethyl-7α,13α-Methano-5H-Naphtho[2',1':4,5]Cyclohepta[1,2-B]Pyridin-5-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.