Description

(1S)-3,3,4α-Trimethyl-4-(4-Methylphenyl)Cyclopentan-1β-Ol CAS NO 24887-33-0 is a high-purity, chiral cyclopentanol derivative characterized by its specific stereochemistry and aromatic substitution. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its structural complexity and potential to impart specific stereochemical outcomes in downstream reactions. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a precursor in the creation of advanced, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Asymmetric Catalysis: Serves as a chiral ligand precursor or a scaffold for developing novel catalysts used in enantioselective synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique optical or mechanical properties.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, stereochemically-defined aroma chemicals.
• Academic & R&D Laboratories: A valuable reference standard and building block for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	(1S)-3,3,4α-Trimethyl-4-(4-Methylphenyl)Cyclopentan-1β-Ol
CAS No.	24887-33-0
Molecular Formula	C15H22O
Molecular Weight	218.33 g/mol
Synonyms	(1S)-3,3,4α-Trimethyl-4-(p-tolyl)cyclopentan-1β-ol; (1S,4R)-3,3,4-Trimethyl-4-(4-methylphenyl)cyclopentan-1-ol; 4-(4-Methylphenyl)-3,3,4α-trimethylcyclopentan-1β-ol; p-Tolyl-substituted chiral cyclopentanol; CAS 24887-33-0; Cyclopentanol, 3,3,4α-trimethyl-4-(4-methylphenyl)-, (1S,4R)-rel-; A chiral cyclopentanol derivative.
EINECS	Contact for details

Quality Control

Our (1S)-3,3,4α-Trimethyl-4-(4-Methylphenyl)Cyclopentan-1β-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles are provided and available upon request, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.