Description

(1S,2R)-1,2-Epoxy-1,2-Dihydronaphthalene is a high-purity chiral epoxide building block of significant importance in asymmetric synthesis. This compound matters because its rigid, fused-ring structure and defined stereochemistry make it a versatile precursor for synthesizing complex, optically active molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of tetralin-based drug candidates, including potential central nervous system (CNS) agents and cardiovascular drugs.
• Asymmetric Catalysis Research: Used as a model substrate in the development and screening of new chiral catalysts for epoxide ring-opening reactions.
• Agrochemical Synthesis: Serves as a building block for creating stereochemically defined active ingredients in herbicides and fungicides.
• Liquid Crystal & Advanced Material Precursor: The rigid, planar naphthalene core is valuable for constructing organic semiconductors and liquid crystal compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(1S,2R)-1,2-Epoxy-1,2-Dihydronaphthalene
CAS No.	24825-00-1
Molecular Formula	C10H8O
Molecular Weight	144.17 g/mol
Synonyms	(1S,2R)-1,2-Epoxytetralin; (1S,2R)-1,2-Dihydronaphthalene 1,2-oxide; (-)-(1S,2R)-1,2-Epoxy-1,2,3,4-tetrahydronaphthalene; (1S,2R)-1,2-Epoxy-1,2,3,4-tetrahydronaphthalene; 1,2-Epoxy-1,2-dihydronaphthalene, (1S,2R)-; Naphthalene, 1,2-epoxy-1,2-dihydro-, (1S,2R)-; Chiral Epoxytetralin
EINECS	Contact for details

Quality Control

Our (1S,2R)-1,2-Epoxy-1,2-Dihydronaphthalene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by chiral HPLC, NMR, and GC analysis to confirm identity, chemical purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and potential polymerization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.