Description

p-Hydroxyphenylglyoxal Monohydrate is a versatile aromatic α-diketone derivative, serving as a key synthetic intermediate and building block in advanced organic synthesis. Its high reactivity, particularly at the glyoxal moiety, makes it invaluable for constructing complex heterocyclic systems and fine-tuning molecular properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic compounds, including potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed as a building block for dyes, pigments, and advanced organic materials requiring specific aromatic-aldehyde functionality.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling proteins or nucleic acids due to its reactive carbonyl groups.
• Cross-linking Agent: Acts as a cross-linker in polymer chemistry and material science for modifying polymer properties.
• Flavor & Fragrance Industry: Serves as an intermediate in the synthesis of complex aroma chemicals.

Basic Information

Product Name	p-Hydroxyphenylglyoxal Monohydrate
CAS No.	24645-80-5
Molecular Formula	C8H8O4 • H2O
Molecular Weight	182.15 g/mol (Monohydrate)
Synonyms	4-Hydroxyphenylglyoxal Monohydrate; (4-Hydroxyphenyl)-2-oxoacetaldehyde Monohydrate; 2-Oxo-2-(4-hydroxyphenyl)acetaldehyde Monohydrate; p-Hydroxybenzoylformaldehyde Monohydrate; 4-Hydroxybenzoylformaldehyde Monohydrate; 4-Hydroxymandelaldehyde Monohydrate (tautomeric form); PHG Monohydrate
EINECS	Contact for details

Quality Control

Our p-Hydroxyphenylglyoxal Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), water content (KF), and identification (IR, NMR). Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Water Content (KF)	8.0% - 11.0% (Theoretical for monohydrate: ~9.9%)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.