Description

8-Fluoro-1-Benzosuberone is a fluorinated benzocycloheptanone derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its unique bicyclic structure, which incorporates a strategically placed fluorine atom, enabling precise modulation of molecular properties for the development of novel compounds. This intermediate is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Synthesis: Used in the preparation of advanced crop protection agents, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers and advanced organic materials with tailored electronic or photophysical properties.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical studies.
• Academic & Contract Research: A critical reagent for methodology development and exploratory synthesis in academic laboratories and CROs (Contract Research Organizations).
• Fluorine Chemistry Library Building: An essential component for constructing diverse compound libraries focused on fluorine-containing molecules for high-throughput screening.

Basic Information

Product Name	8-Fluoro-1-Benzosuberone
CAS No.	24484-21-7
Molecular Formula	C11H11FO
Molecular Weight	178.20 g/mol
Synonyms	8-Fluoro-2,3,4,5-tetrahydro-1-benzocyclohepten-1-one; 8-Fluorobenzosuberone; 1-Benzosuberone, 8-fluoro-; 8-Fluoro-2,3,4,5-tetrahydro-1H-1-benzocyclohepten-1-one; 8-Fluoro-2,3,4,5-tetrahydrobenzo[b]azepin-1-one; 24484-21-7 (CAS); Fluorobenzosuberone
EINECS	Contact for details

Quality Control

Our 8-Fluoro-1-Benzosuberone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.