Description

(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzene is a high-purity organoboron reagent, specifically a pinacol phenylboronic ester, widely used as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex aromatic and heteroaromatic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific phenyl-substituted architectures.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Suzuki-Miyaura Cross-Coupling Reactions: The primary application is as a stable, air-tolerant boronic ester partner for palladium-catalyzed coupling with aryl halides or triflates.
• Chemical Research & Development: An indispensable tool in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzene
CAS No.	24388-23-6
Molecular Formula	C12H17BO2
Molecular Weight	204.08 g/mol
Synonyms	Phenylboronic Acid Pinacol Ester; Phenylpinacolborane; Phenyl-Bpin; 2-Phenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzeneboronic Acid Pinacol Ester; Phenylboronic Ester; Phenyl-B(pin); B-Phenylpinacolboronate
EINECS	Contact for details

Quality Control

Our (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be stored away from strong alkali and incompatible organic solvents. For long-term storage, consider keeping the container under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	86 - 90 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.