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6-Amino-6-Deoxy-1,2-o-Isopropylidene-α-D-Glucofuranose Hydrochloride CAS NO 24384-87-0


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CAS No.:24384-87-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Amino-6-Deoxy-1,2-o-Isopropylidene-α-D-Glucofuranose Hydrochloride is a protected amino sugar derivative, a crucial chiral building block in organic synthesis. Its primary value lies in its role as a key intermediate for the production of more complex bioactive molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing nucleoside analogs, antibiotics, and other glycosylated therapeutics.

Application

  • Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of nucleoside analogs and antiviral/antibiotic agents.
  • Glycochemistry Research: Used in the study and synthesis of complex carbohydrates, glycoconjugates, and glycomimetics.
  • Bioconjugate Chemistry: Serves as a starting material for creating labeled sugars or sugar-protein conjugates for diagnostic and research applications.
  • Chemical Biology Probes: Employed in the development of molecular probes to study glycosylation processes and carbohydrate-protein interactions.
  • Process Development: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) requiring specific sugar moieties.

Basic Information

Product Name 6-Amino-6-Deoxy-1,2-o-Isopropylidene-α-D-Glucofuranose Hydrochloride
CAS No. 24384-87-0
Molecular Formula C9H18ClNO5
Molecular Weight 255.70 g/mol
Synonyms 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 6-amine hydrochloride; 6-Amino-6-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose hydrochloride; 6-Amino-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose hydrochloride; 6-Deoxy-6-amino-1,2-O-isopropylidene-α-D-glucofuranose hydrochloride; D-Glucofuranose, 6-amino-6-deoxy-1,2-O-(1-methylethylidene)-, hydrochloride, α-; 6-Amino-6-deoxy-di-O-isopropylidene-α-D-glucofuranose HCl
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Quality Control

Our 6-Amino-6-Deoxy-1,2-o-Isopropylidene-α-D-Glucofuranose Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Opened containers should be flushed with an inert gas and resealed immediately.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Specific Rotation [α]20/D -20° to -25° (c=1 in H2O)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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